Tuesday, June 29, 2010

PARA COMPREENDER!

https://docs.google.com/viewer?attid=0.1&pid=gmail&thid=129801046e70ef48&url=https%3A%2F%2Fmail.google.com%2Fmail%2F%3Fui%3D2%26ik%3D8369aea477%26view%3Datt%26th%3D129801046e70ef48%26attid%3D0.1%26disp%3Dattd%26zw&docid=401b00304b82ec9c68ad4319470892bd%7C428b9a308e17db45139afa7c243d4f96&a=bi&pagenumber=1&w=800

Para compreenderes

o valor de uma Irmã,
pergunta a alguém
que não tem nenhuma
ou que a perdeu.
Para compreenderes
o valor de 10 anos,
pergunta a um casal
recém divorciado.
Para comprenderes
o valor de 4 anos,
pergunta a um
recém-formado.
Para compreenderes
o valor de 1 ano,
pergunta a um estudante
que reprovou no exame final.
Para compreenderes
o valor de 9 meses,
pergunta a uma Mãe
que acaba de
dar a luz um filho.
Para compreenderes
o valor de 1 mês,
pergunta a uma Mãe
que acaba de dar à luz
um bébé prematuro.
Para compreenderes
o valor de 1 semana,
pergunta a um editor
dum jornal semanal.
Para compreenderes
o valor de 1 minuto,
pergunta a alguém
que perdeu o combóio,
o autocarro ou o avião.
Para compreenderes
o valor de 1 segundo,
pergunta a alguém
que tenha sobrevivido
a um acidente.
Porque…
para compreenderes
o valor de um Amigo ou
dum ente Querido,
basta PERDÊ-LO.

https://docs.google.com/viewer?attid=0.1&pid=gmail&thid=129801046e70ef48&url=https%3A%2F%2Fmail.google.com%2Fmail%2F%3Fui%3D2%26ik%3D8369aea477%26view%3Datt%26th%3D129801046e70ef48%26attid%3D0.1%26disp%3Dattd%26zw&docid=401b00304b82ec9c68ad4319470892bd%7C428b9a308e17db45139afa7c243d4f96&a=bi&pagenumber=19&w=800

OBRIGADA MARIA PELO CARINHO. AMEI!!!



JÁ HAVIA POSTADO ESTE LINDO PRESENTE EM MEUS MIMOS. MAS AGORA VOU OFERECER A TODOS. SEUS BLOGS TAMBÉM FAZEM A DIFERENÇA. POIS JUNTOS APRENDEMOS, TROCAMOS E CONFRATERNIZAMOS UMA GRANDE AMIZADE, ALÉM DE UMA GRANDE DIVERSIDADES DE IDEIAS.


Ganhei este lindo selinho da amiga Anninha


NÃO DEIXE CONFERI... COMPARTILHE ..


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MEUS MIMOS
OFERECIDOS/RECEBIDOS.

Monday, June 28, 2010

O MEU OLHAR!!

Ganhei este lindo poema do amigo Carlos.
Obrigada amigo.

AGRADEÇO IMENSAMENTE A ROSA. AMO FLORES..

FERNANDO
PESSOA

Poemas de
Alberto Caeiro
II - O Meu Olhar

    O meu olhar é nítido como um girassol.
    Tenho o costume de andar pelas estradas
    Olhando para a direita e para a esquerda,
    E de vez em quando olhando para trás...
    E o que vejo a cada momento
    É aquilo que nunca antes eu tinha visto,
    E eu sei dar por isso muito bem...
    Sei ter o pasmo essencial
    Que tem uma criança se, ao nascer,
    Reparasse que nascera deveras...
    Sinto-me nascido a cada momento
    Para a eterna novidade do Mundo...

    Creio no mundo como num malmequer,
    Porque o vejo. Mas não penso nele
    Porque pensar é não compreender...

    O Mundo não se fez para pensarmos nele
    (Pensar é estar doente dos olhos)
    Mas para olharmos para ele e estarmos de acordo...

    Eu não tenho filosofia; tenho sentidos...
    Se falo na Natureza não é porque saiba o que ela é,
    Mas porque a amo, e amo-a por isso
    Porque quem ama nunca sabe o que ama
    Nem sabe por que ama, nem o que é amar...

    Amar é a eterna inocência,
    E a única inocência não pensar...

    Alberto Caeiro, em "O Guardador de Rebanhos", 8-3-1914
NÃO DEIXE CONFERI... COMPARTILHE ..


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When One Neurotransmitter Is Not Enough

Important news from San Francisco neuroscientists Stuber et al: Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate.

The finding's right there in the title: dopamine is a neurotransmitter, and so is glutamate. Stuber et al found (in mice) that many of the cells that release dopamine also simultaneously release glutamate - specifically, almost all of the cells that project to the nucleus accumbens, involved in pleasure and motivation, also release glutamate. By contrast none of the dopaminergic neurons projecting to the nearby dorsal striatum, involved in movement regulation do this.

Previous work had provided some suggestive evidence for some degree of glutamate/dopamine co-release but this is the first hard evidence and the fact that basically all the dopamine input to the nucleus accumbens is also glutamate input is especially striking.

This is important because it overturns the idea that neurons only release one neurotransmitter each. In fact, it's been clear for a while that this isn't strictly true: there are various little-understood peptide transmitters or "neurohormones" that are known to be co-released, but their function is obscure in most cases.

Dopamine and glutamate on the other hand are both extremely well studied neurotransmitters in their own right. Glutamate's the single most common transmitter in the brain while dopamine is famous for its role in motor control, motivation, Parkinson's disease, mental illness and the action of recreational drugs, just for starters.

What exactly the glutamate does in the nucleus accumbens is completely mysterious at present but future work will no doubt shed light on this. More generally, this paper is a reminder of the fact that our knowledge of the brain is still in its infancy...

ResearchBlogging.orgStuber, G., Hnasko, T., Britt, J., Edwards, R., & Bonci, A. (2010). Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate Journal of Neuroscience, 30 (24), 8229-8233 DOI: 10.1523/JNEUROSCI.1754-10.2010

When One Neurotransmitter Is Not Enough

Important news from San Francisco neuroscientists Stuber et al: Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate.

The finding's right there in the title: dopamine is a neurotransmitter, and so is glutamate. Stuber et al found (in mice) that many of the cells that release dopamine also simultaneously release glutamate - specifically, almost all of the cells that project to the nucleus accumbens, involved in pleasure and motivation, also release glutamate. By contrast none of the dopaminergic neurons projecting to the nearby dorsal striatum, involved in movement regulation do this.

Previous work had provided some suggestive evidence for some degree of glutamate/dopamine co-release but this is the first hard evidence and the fact that basically all the dopamine input to the nucleus accumbens is also glutamate input is especially striking.

This is important because it overturns the idea that neurons only release one neurotransmitter each. In fact, it's been clear for a while that this isn't strictly true: there are various little-understood peptide transmitters or "neurohormones" that are known to be co-released, but their function is obscure in most cases.

Dopamine and glutamate on the other hand are both extremely well studied neurotransmitters in their own right. Glutamate's the single most common transmitter in the brain while dopamine is famous for its role in motor control, motivation, Parkinson's disease, mental illness and the action of recreational drugs, just for starters.

What exactly the glutamate does in the nucleus accumbens is completely mysterious at present but future work will no doubt shed light on this. More generally, this paper is a reminder of the fact that our knowledge of the brain is still in its infancy...

ResearchBlogging.orgStuber, G., Hnasko, T., Britt, J., Edwards, R., & Bonci, A. (2010). Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate Journal of Neuroscience, 30 (24), 8229-8233 DOI: 10.1523/JNEUROSCI.1754-10.2010

Saturday, June 26, 2010

Password

A few days ago, a friend of mine had her GMail account compromised, resulting in much stress for all concerned. This prompted me to change my passwords.

That was three days ago. Since then, I've logged into GMail maybe ten or fifteen times, and every single time I've initially typed the old password. Sometimes, I catch myself and change it before hitting "enter", but usually not. Access denied. Oops. It's getting slightly better, but I think it'll be a good few days before I'm entering the new password as automatically as I did the old one.

It's not hard to see why this kind of thing happens: I'd typed in the old password hundreds, probably thousands, of times over the course of at least a year. It had become completely automatic. That kind of habit takes a long time to learn, so it's no surprise that it takes quite a while to unlearn (though hopefully not quite as long).

Psychologists will recognize the distinction between declarative memory, my concious knowledge of what my new password is, and procedural memory, my ability to unconsciously type it. It's also commonly known as "muscle memory": this is misleading because it's stored in the brain, like all knowledge, but it nicely expresses the feeling that it's your body that has the memory, rather than "you".

Damage to the hippocampus can leave people unable to remember what happened ten minutes ago, but perfectly capable of learning new skills: they just don't remember how they learned them. But you don't have to suffer brain damage to experience procedural knowledge in the absence of declarative recall. I've sometimes found myself unable to remember my password and only reminded myself by going to the login page and successfully typing it. I knew it all along - but only procedurally.

The thing about procedural knowledge is that when it works, you don't notice it's there. So we almost certainly underestimate its contribution to our lives. If you asked me what happens when I log in to GMail, I'd probably say "I type in my username and my password". But maybe it would be more accurate to say: "I go to the login screen, and my brain types my username and password."

Can I take the credit, given that sometimes I - my conciousness - don't even know the password until my brain's helpfully typed it for me? And while in this case I do know it some of the time, much of our procedural knowledge has no declarative equivalent. I can ride a bike, but if you asked me to tell you how I do it, to spell out the complex velocity-weight-momentum calculations that lie behind the adjustments that my muscles constantly make to keep me upright, I'd be stumped.

"I just sit down and pedal." But if I literally did that and nothing more, I'd fall flat on my face. There's a lot more to cycling than that, but I have no idea what it is. So can I ride a bike, or do I just happen to inhabit a brain that can? Isn't saying that I can ride a bike like saying that I can drive just because I have a chauffeur?


Take this train of thought far enough and you reach some disturbing conclusions. Maybe it's not so hard to accept that various skills lie outside the reach of our concious self, but surely the decisions to use those skills are ours alone. Sure, my brain types my username and password for me, but I'm the one who decided to login to GMail - I could have decided to turn the computer off and go for a walk instead. I have Free Will! Like George W. Bush, I'm the Decider. My brain just handles the boring details.

But isn't deciding a skill too? And willing, remembering, thinking, judging, feeling, concluding - I can do all those things, but if I knew how I do them, I'd win the the Nobel Prize in Physiology or Medicine because I'd just have solved the hardest questions of neuroscience. So can I take credit for doing them, or is it my brain?

Ultimately, every concious act must be constructed from unconscious processes; otherwise there would be an infinite regress of conciousness. If the world rested on the back of a giant turtle, what would the turtle stand on? Turtles all the way down?

Link: The Concept of Mind (1949) is a book by the British philosopher Gilbert Ryle, from which I "borrowed" the ideas in this post, and which was probably the one book that most inspired me to study neuroscience.

Password

A few days ago, a friend of mine had her GMail account compromised, resulting in much stress for all concerned. This prompted me to change my passwords.

That was three days ago. Since then, I've logged into GMail maybe ten or fifteen times, and every single time I've initially typed the old password. Sometimes, I catch myself and change it before hitting "enter", but usually not. Access denied. Oops. It's getting slightly better, but I think it'll be a good few days before I'm entering the new password as automatically as I did the old one.

It's not hard to see why this kind of thing happens: I'd typed in the old password hundreds, probably thousands, of times over the course of at least a year. It had become completely automatic. That kind of habit takes a long time to learn, so it's no surprise that it takes quite a while to unlearn (though hopefully not quite as long).

Psychologists will recognize the distinction between declarative memory, my concious knowledge of what my new password is, and procedural memory, my ability to unconsciously type it. It's also commonly known as "muscle memory": this is misleading because it's stored in the brain, like all knowledge, but it nicely expresses the feeling that it's your body that has the memory, rather than "you".

Damage to the hippocampus can leave people unable to remember what happened ten minutes ago, but perfectly capable of learning new skills: they just don't remember how they learned them. But you don't have to suffer brain damage to experience procedural knowledge in the absence of declarative recall. I've sometimes found myself unable to remember my password and only reminded myself by going to the login page and successfully typing it. I knew it all along - but only procedurally.

The thing about procedural knowledge is that when it works, you don't notice it's there. So we almost certainly underestimate its contribution to our lives. If you asked me what happens when I log in to GMail, I'd probably say "I type in my username and my password". But maybe it would be more accurate to say: "I go to the login screen, and my brain types my username and password."

Can I take the credit, given that sometimes I - my conciousness - don't even know the password until my brain's helpfully typed it for me? And while in this case I do know it some of the time, much of our procedural knowledge has no declarative equivalent. I can ride a bike, but if you asked me to tell you how I do it, to spell out the complex velocity-weight-momentum calculations that lie behind the adjustments that my muscles constantly make to keep me upright, I'd be stumped.

"I just sit down and pedal." But if I literally did that and nothing more, I'd fall flat on my face. There's a lot more to cycling than that, but I have no idea what it is. So can I ride a bike, or do I just happen to inhabit a brain that can? Isn't saying that I can ride a bike like saying that I can drive just because I have a chauffeur?


Take this train of thought far enough and you reach some disturbing conclusions. Maybe it's not so hard to accept that various skills lie outside the reach of our concious self, but surely the decisions to use those skills are ours alone. Sure, my brain types my username and password for me, but I'm the one who decided to login to GMail - I could have decided to turn the computer off and go for a walk instead. I have Free Will! Like George W. Bush, I'm the Decider. My brain just handles the boring details.

But isn't deciding a skill too? And willing, remembering, thinking, judging, feeling, concluding - I can do all those things, but if I knew how I do them, I'd win the the Nobel Prize in Physiology or Medicine because I'd just have solved the hardest questions of neuroscience. So can I take credit for doing them, or is it my brain?

Ultimately, every concious act must be constructed from unconscious processes; otherwise there would be an infinite regress of conciousness. If the world rested on the back of a giant turtle, what would the turtle stand on? Turtles all the way down?

Link: The Concept of Mind (1949) is a book by the British philosopher Gilbert Ryle, from which I "borrowed" the ideas in this post, and which was probably the one book that most inspired me to study neuroscience.

BOM FINAL DE SEMANA A TODOS!!

AS VEZES PRECISAMOS REPENSAR ALGUMAS COISAS. A VIDA NOS MOSTRA MUITAS POSSIBILIDADES.. VEJA A GRANDEZA DESTE FILME!



FINAL DE SEMNA CHEGANDO...FICAMOS ASSIM...COM VONTADE DE DORMIR UM POUQUINHO MAIS!!!!!!!MERECEMOS, NÃO É MESMO!!!!!!!!





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